Lawrence Livermore National Laboratory



Bruce Buchholz
NIH Resource for Biomedical AMS
Center for Accelerator Mass Spectrometry
Lawrence Livermore National Laboratory
7000 East Avenue, L-397
Livermore, CA 94550

Ken Turteltaub
NIH Resource for Biomedical AMS
Biosciences and Biotechnology Division
Lawrence Livermore National Laboratory
7000 East Avenue, L-452
Livermore, CA 94550

An acknowledgment will be sent to the principal investigator when the application is received. The Application will initially be examined to determine if it is complete. Questions about the application should be referred to the Resource Administrator. For proposals involving vertebrate animals, LLNL Institutional Animal Care and Use Committee (IACUC) requires an additional form: "Vertebrate Animal Use Notification and Approval" form, available in both PDF and MS Word. For proposals involving Human Subjects, the applicant must discuss the LLNL Institutional Review Board (IRB) approval requirements with the Resource staff. Indicate on the application if IRB approvals are still pending. Applications that are not complete will be returned for revision.

Once complete, the application is reviewed by the Resource Proposal Review Panel to determine if the research problem is appropriate for AMS or if other techniques are better suited to study the problem. The Proposal Review Panel also determines whether the proposed project should be a Service or Collaborative endeavor. The Panel may make suggestions for improvements of the proposal to maximize the scientific value of the AMS measurements. If the proposal is significantly flawed, it will be returned to the proposal principal investigator with comments detailing the apparent shortcomings.

If the reviewed proposal is approved, the principal investigator will receive notification by email and be assigned an RR Project number. The RR Project number should be used on all future communication with the Resource about the project. The Resource Administrator is the primary contact for co-coordinating all aspects of the Project including IACUC and IRB approvals, business arrangements for measurement costs, sample submissions, updating Project information and other administrative purposes. A scientific contact for the project will be appointed from Resource staff. They will be available for consultation on experiment design, sample preparation and data analysis.

A single experiment project is valid for up to two years, subject to annual review, from the date of its approval by the Resource. A project can be renewed for a second 2-year period after an updated application is submitted and reviewed. The update review will take into consideration the progress to date on the project and continuing scientific priority. For NIH/NCRR annual reporting requirements, project information will be reviewed and updated annually. For NIH reporting purposes, we require that all publications be deposited in Pubmed Central. If deposition is not done by the journal, the primary or corresponding author should deposit the papers.

Questions about the application should be referred to the Resource Administrative Contact, .