Lawrence Livermore National Laboratory



Hummel, J.M., Madeen, E.P., Siddens, L.K., Uesugi, S.L., McQuistan, T., Anderson, K.A., Turteltaub, K.W., Ognibene, T.J., Bench, G., Krueger, S.K., Harris, S., Smith, J., Tilton, S.C., Baird, W.M., Williams, D.E. (2018), Pharmacokinetics of [14C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction, Food Chem. Toxicol. 115, 136–147. doi: 10.1016/j.fct.2018.03.003. [Epub ahead of print] PubMed PMID: 29518434.


Zimmermann, M., Wang, S.S., Zhang, H., Lin, T.Y., Malfatti, M., Haack, K., Ognibene, T., Yang, H., Airhart, S., Turteltaub, K.W., Cimino, G.D., Tepper, C.G., Drakaki, A., Chamie, K., de Vere White, R., Pan, C.X., Henderson, P.T. (2017), Microdose-Induced Drug-DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice, Mol. Cancer Ther. 16 (2), 376–38. PMID:27903751.


Wang, Y., Villalta, P.W., Peng, L., Dingley, K., Malfatti, M.A., Turteltaub, K.W., Turesky, R.J. (2017), Mass Spectrometric Characterization of an Acid-Labile Adduct Formed with 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and Albumin in Humans, Chem. Res. Toxicol. 30 (2), 705–714. doi: 10.1021/acs.chemrestox.6b00426. Epub 2017, Jan. 18. PubMed PMID: 27984695.


Malfatti, M.A., Kuhn, E.A., Turteltaub, K.W., Vickers, S.M., Jensen, E.H., Strayer, L., Anderson, K.E. (2016), Disposition of the Dietary Mutagen 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline in Healthy and Pancreatic Cancer Compromised Humans, Chem. Res. Toxicol. 29 (3), 352–8. doi: 10.1021/acs.chemrestox.5b00495. Epub 2016, Mar. 8. PubMed PMID: 26918625.


Madeen, E.P., Ognibene, T.J., Corley, R.A., McQuistan, T.J., Henderson, M.C., Baird, W.M., Bench, G., Turteltaub, K.W., Williams, D.E. (2016), Human Microdosing with Carcinogenic Polycyclic Aromatic Hydrocarbons: In Vivo Pharmacokinetics of Dibenzo[def,p]chrysene and Metabolites by UPLC Accelerator Mass Spectrometry, Chem. Res. Toxicol. 29 (10) 1641–1650. Epub 2016, Sep. 9. PubMed PMID: 27494294.


Cai, H., Scott, E., Kholghi, A., Andreadi, C., Rufini, A., Karmokar, A., Britton, R.G., Horner-Glister, E., Greaves, P., Jawad, D., James, M., Howells, L., Ognibene, T., Malfatti, M., Goldring, C., Kitteringham, N., Walsh, J., Viskaduraki, M., West, K., Miller, A., Hemingway, D., Steward, W.P., Gescher, A.J., Brown, K. (2015), Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice, Sci. Transl. Med. 7 (298), 298ra117. doi: 10.1126/scitranslmed.aaa7619. PubMed PMID: 26223300.


Buchholz, B.A., Sarachine Falso, M.J., Stewart, B.J., Haack, K.W., Ognibene, T.J., Bench, G., Salazar Qunitero, G.A., Malfatti, M.A., Kulp, K.S., and Turteltaub, K.W. (2012), Bioanalytics for Human Microdosing, Encyclopedia of Drug Metabolism and Interactions, IX, 1–28, ISBN: 978-0-470-45015-4, doi: 10.1002/9780470921920.edm112
http://onlinelibrary.wiley.com/doi/10.1002/9780470921920.edm112/pdf


Jubert, C., Mata, J., Bench, G., Dashwood, R., Pereira, C., Tracewell, W., Turteltaub, K., Williams, D., and Bailey, G. (2009), Effects of chlorophyll and chlorophyllin on low-dose aflatoxin B1 pharmacokinetics in human volunteers: A pilot study, Cancer Prevention Research 2 (12), 1015, doi: 10.1158/1940-6207.CAPR-09-0099
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314947/


Brown, K., Tompkins, E.M., Boocock, D.J., Martin, E.A., Farmer, P.B., Turteltaub, K.W., Ubick, E., Hemingway, D., Horner-Glister, E., and White, I.N. (2007), Tamoxifen forms DNA adducts in human colon after administration of a single [14C]-labeled therapeutic dose, Cancer Research 67 (14), 6995, doi: 10.1158/0008-5472.CAN-07-0913
http://cancerres.aacrjournals.org/content/67/14/6995.full.pdf


Carkeet, C., Dueker, S.R., Lango, J., Buchholz, B.A., Miller, J.W., Green, R., Hammock, B.D., Roth, J.R., and Anderson, P.J. (2006), Human vitamin B12 absorption measurement by accelerator mass spectrometry using specifically labeled 14C-cobalamin, Proc. Natl. Acad. Sci, USA, 103, 5694, doi: 10.1073/pnas.0601251103
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458365/


Lin, Y.M., Dueker, S.R., Follett, J.R., Fadel, J.G., Arjomand, A., Schneider, P.D., Miller, J.W., Green, R., Buchholz, B.A., Vogel, J.S., Phair, R.D., and Clifford, A.J. (2004), Quantitation of in vivo human folate metabolism, American Journal Of Clinical Nutrition 80, 680, https://www.ncbi.nlm.nih.gov/pubmed/15321809


Lemke, S.L., Dueker, S.R., Follett, J.R., Lin, Y., Carkeet, C., Buchholz, B.A., Vogel, J.S., and Clifford, A.J. (2003), Absorption and retinol equivalence of beta-carotene in humans is influenced by dietary vitamin A intake, Journal of Lipid Research 44, 1591, doi: 10.1194/jlr.M300116-JLR200
https://www.ncbi.nlm.nih.gov/pubmed/12777466


Buchholz, B.A., Fultz, E., Haack, K.W., Vogel, J.S., Gilman, S.D., Gee, S., Hammock, B.D., Hui, X., Wester, R.C., and Maibach, H.I. (1999), HPLC-AMS Measurement of Atrazine Metabolites in Human Urine after Dermal Exposure, Analytical Chemistry 71, 3519, doi: 10.1021/ac990152g
http://pubs.acs.org/doi/full/10.1021/ac990152g
https://www.ncbi.nlm.nih.gov/pubmed/10464479


Dingley, K.H., Curtis, K.D., Nowell, S., Felton, J.S., Lang, N.P., Turteltaub, K.W. (1999), DNA and protein adduct formation in the colon and blood of humans after exposure to a dietary-relevant dose of 2-amino-1-methyl-6-phenylimidazo 4,5-b pyridine, Cancer Epidemiology Biomarkers & Prevention 8 (6), 507, https://www.ncbi.nlm.nih.gov/pubmed/10385140


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